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Learn about its more common, mild, and serious side effects and how to manage them Januvia ( sitagliptin ), from Merck, works by targeting two key problems in type 2 diabetes: it increases insulin production in the pancreas and decreases glucose overproduction in the liver. Issued: October 24, 2006 Where is Januvia made? The active pharmaceutical ingredient was formulated in Italy Januvia is an oral diabetes medicine that helps control blood sugar levels. If you have had pancreatitis (inflammation of the pancreas), it is not known if you have a higher chance of getting it while. Januvia is a type of drug called a dipeptidyl peptidase-4 (DPP-4) inhibitor. A1C is a blood test that shows the average amount of sugar (glucose) in your blood over the past 2 to 3 months, letting you know how well your blood sugar is being controlled over time The Januvia package reads “Formulated in UK. The Januvia package also states “Sitagliptin (active ingred. 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